Andrea Ortega lifted a sacrifice fly to quickly push the Dogs - who were the designated visiting team - in front for an early 1-0 lead.
Courntey Moore extended Fresno State's lead to 2-0 with a sixth-inning rainbow solo shot over the right field chain-linked fence.
Junior pitcher Michelle Moses back contained a potent Hawai'i offense and allowed only a run in the sixth as the Dogs cruised to the 2-1 victory.
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